Components of the PANBioRa biomaterial risk assessment system

ANTIBODY TESTING

Patient-specific interactions between biomaterials and the immune system will be assessed using the ground-breaking Mimotope Variation Analysis technology.

BIOMATERIAL TESTING

Biochemical responses of cells to the presence of biomaterials will be monitored in real time and by integrated biosensors. In addition, PANBioRA includes cytotoxicity and genotoxicity tests with microscopic real-time monitoring capacities

CELL TESTING

Real-time electrochemical sensing will be used to determine the cellular response to a given biomaterial. A set of cytokines released to the extracellular environment will be used as biomarkers to assess the cell response to different biomaterials.

ORGAN ON A CHIP

Respiratory epithelium, gut and liver tissues will be miniaturized into organoids on chip to allow the determination of possible systemic and target organ-specific effects in both healthy and disease conditions.

Components of the PANBioRA biomaterial risk assessment system

SIMULATIONS

Potential risks that are difficult to assess experimentally – such as explosion hazards or full-scale biomaterial/microbiota interactions - will be covered by simulations developed within the project.

DATA ANALYSIS

The readouts of the modules will be fed into a model developed within PANBioRA using known biocompatible and hazardous materials to provide a quantitative risk assessment.

RISK RATING

PANBioRA will develop a risk rating system that will display the suitability of the tested biomaterial.

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ABOUT PANBioRA

PROJECT NEWS

PANBioRA M18 periodic review meeting

From 3-5 June the PANBioRA consortium meets in Brussesl to present their research activities performed during the first 18 months of the project.

PANBioRA at International Conference on Medical and Biological Engineering 2019

PANBioRA partner Steinbeis Advanced Risk Technologies Institute Doo Kragujevac was present at the CMBEBIH 2019 in Banja Luka, Bosnia and Herzegovina |16-18 May 2019|

New PANBioRA scientific publications available

PANBioRA partners INSERM and Protip have released new scientific publications!

Upcoming Events

24.-26. June 2019

7th international congress of Serbian Society of Mechanics

in Sremski Karlovci, Serbia

The increasing necessity to solve complex problems in Theoretical and Applied Mechanics requires the development of new ideas and innovative methods for providing solutions.

25.-26. June 2019