Components of the PANBioRa biomaterial risk assessment system

ANTIBODY TESTING
Patient-specific interactions between biomaterials and the immune system will be assessed using the ground-breaking Mimotope Variation Analysis technology.
ANTIBODY TESTING
BIOMATERIAL TESTING
Biochemical responses of cells to the presence of biomaterials will be monitored in real time and by integrated biosensors. In addition, PANBioRA includes cytotoxicity and genotoxicity tests with microscopic real-time monitoring capacities
BIOMATERIAL TESTING
CELL TESTING
Real-time electrochemical sensing will be used to determine the cellular response to a given biomaterial. A set of cytokines released to the extracellular environment will be used as biomarkers to assess the cell response to different biomaterials.
CELL TESTING
ORGAN ON A CHIP
Respiratory epithelium, gut and liver tissues will be miniaturized into organoids on chip to allow the determination of possible systemic and target organ-specific effects in both healthy and disease conditions.
ORGAN ON A CHIP
SIMULATIONS
SIMULATIONS
Potential risks that are difficult to assess experimentally – such as explosion hazards or full-scale biomaterial/microbiota interactions - will be covered by simulations developed within the project.
Data Analysis
DATA ANALYSIS
The readouts of the modules will be fed into a model developed within PANBioRA using known biocompatible and hazardous materials to provide a quantitative risk assessment.
RISK RATING
RISK RATING
PANBioRA will develop a risk rating system that will display the suitability of the tested biomaterial.

PROJECT NEWS

Is your research areas in the field of 3D printing of personalized medical implants (metals, ceramics and polymers) or medical devices? Submit your article until 15 April

 

Are you an expert working in the field of "biomaterials", "implants", "medical devices", "risk analysis", "multiscale modelling", "policies & regulations" or related fields?

Partners involved in WP 4 met for fruitful discussions in Barcelona

Upcoming Events

in Venice, Italy

Training School on the new generation of nano-environmental, health and safety.

in Brussels, Belgium

Join industrial producers of nanomaterials, expert service providers, end-users, policy makers and regulators at NIA’s 8th Annual Symposium, for a day of presentations, discussion and networking.

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