Components of the PANBioRa biomaterial risk assessment system

ANTIBODY TESTING

Patient-specific interactions between biomaterials and the immune system will be assessed using the ground-breaking Mimotope Variation Analysis technology.

BIOMATERIAL TESTING

Biochemical responses of cells to the presence of biomaterials will be monitored in real time and by integrated biosensors. In addition, PANBioRA includes cytotoxicity and genotoxicity tests with microscopic real-time monitoring capacities

CELL TESTING

Real-time electrochemical sensing will be used to determine the cellular response to a given biomaterial. A set of cytokines released to the extracellular environment will be used as biomarkers to assess the cell response to different biomaterials.

ORGAN ON A CHIP

Respiratory epithelium, gut and liver tissues will be miniaturized into organoids on chip to allow the determination of possible systemic and target organ-specific effects in both healthy and disease conditions.

Components of the PANBioRA biomaterial risk assessment system

SIMULATIONS

Potential risks that are difficult to assess experimentally – such as explosion hazards or full-scale biomaterial/microbiota interactions - will be covered by simulations developed within the project.

DATA ANALYSIS

The readouts of the modules will be fed into a model developed within PANBioRA using known biocompatible and hazardous materials to provide a quantitative risk assessment.

RISK RATING

PANBioRA will develop a risk rating system that will display the suitability of the tested biomaterial.

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ABOUT PANBioRA

PROJECT NEWS

PANBioRA at International Conference on Medical and Biological Engineering 2019

PANBioRA partner Steinbeis Advanced Risk Technologies Institute Doo Kragujevac was present at the CMBEBIH 2019 in Banja Luka, Bosnia and Herzegovina |16-18 May 2019|

New PANBioRA scientific publications available

PANBioRA partners INSERM and Protip have released new scientific publications!

PANBioRA at T4M trade fair in Stuttgart

T4M, the new trade fair for technology for medical devices, will open its doors for the first time from 7 to 9 May 2019. The exhibition will focus on production technology, production environment,...

Upcoming Events

21.-23. May 2019

MedtecLIVE 2019

in Nuremberg, Germany

MT-CONNECT and Medtec Europe are pooling their expertise to create a new trade fair with a distinct focus on the entire medical technology supply chain --> MedtecLIVE

27.-31. May 2019

Spring Meeting of the European Materials Research Society (E-MRS)

in Nice, France

The 2019 Spring Meeting of the European Materials Research Society (E-MRS) will take place from May 27 to 31, 2019, in Nice, France (Congress & Exhibition Centre Acropolis). It will be the 37th of the...

27.-31. May 2019